Affinity DataIC50: 0.129nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at EP1 receptor (unknown origin) by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity at EP1 receptor (unknown origin) by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.630nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Antagonist activity at EP1 receptor (unknown origin) by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.790nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 0.790nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Rattus norvegicus (Rat))
Kyorin Pharmaceutical
Curated by ChEMBL
Kyorin Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity at rat EP1 receptor expressed in African green monkey COS1 cells assessed as inhibition of prostaglandin-E2-induced increase in i...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]GW875240X from human prostanoid EP1 receptor expressed in CHO-K1 cells after 45 mins by topcount liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Displacement of [3H]PGE2 from EP1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.51nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHOK1 cell membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Displacement of [3H]PGE2 from EP1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMT: 2°CAssay Description:The cells expressing mouse EP1 receptor were seeded at 104 cells/well in 96-well plates and cultured for 2 days with 10% Fetal Bovine Serum (FBS)/alp...More data for this Ligand-Target Pair
Affinity DataIC50: 3.98nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.98nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.98nMAssay Description:Displacement of [3H]GW875240X from human prostanoid EP1 receptor expressed in CHO-K1 cells after 45 mins by topcount liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]PGE2 from human recombinant EP1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair